Serum Levels of Glutamate-Pyruvate Transaminase, Glutamate-Oxaloacetate Transaminase and Gamma-Glutamyl Transferase in 1494 Patients with Various Genotypes for the Alpha-1 Antitrypsin Gene
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چکیده
منابع مشابه
Effects of Vitamin B6 on the Brain Glutamate Pyrovate Transaminase and Glutamate Oxaloacetate Transaminase in Young and Old Rats
Excessive amounts of extracellular glutamate in brain are excitotoxic and lead to neuronal death. Glutamate pyrovate transamiase (GPT) and glutamate oxaloacetate transaminase (GOT) catalyze transamination of glutamate to alpha ketoglutarate. Because vitamin B6 is essential for the enzymes activities, this study was undertaken to examine the effect of vitamin B6 on age related changes of this en...
متن کاملDetermination of the Chromosomal Location of a Glutamate Oxaloacetate Transaminase Structural Gene Using Triticum-agropyron Translocations1
The glutamate oxaloacetate transaminase (GOT) zymogram phenotypes of a series of 15 translocation lines, a chromosome addition line and a chromosome substitution line were determined. In each of the translocation lines a segment of the long arm of Triticum aestivum chromosome 3D has been replaced by a portion of an Agropyron elongatum homoeologue. Evidence was obtained that the products of the ...
متن کاملAssessment of Serum Enzymes Gamma Glutamyl Trasnferase, Aspartate Transaminase and Alanine Transaminase in Liver Diseases
Back Ground:Liver diseases are common disorders encountered in clinical practices. Investigations in liver diseases are used to detect hepatic abnormality, to measure its severity, to define it structural effect on the liver, to look for specific causes of liver diseases, assess prognosis and to evaluate therapy. Aim and Objectives:To study and compare the altered serum levels of enzymes GGT, A...
متن کاملGlutamate oxaloacetate transaminase (got) genetics in the mouse: polymorphism of got-1.
We have examined a polymorphism for the soluble glutamate oxaloacetate (GOT-1) isozyme system which was found in the Asian mouse Mus castaneus. Variants of GOT-1 segregate as though they are controlled by codominant alleles for a single autosomal locus which we have designated Got-1. No close linkage of genes for soluble and mitochondrial forms of the enzyme, GOT-1 and GOT-2 respectively, was o...
متن کاملSerum gamma glutamyl transferase and alanine transaminase concentrations predict endothelial dysfunction in patients with non-alcoholic steatohepatitis
PURPOSE Cardiovascular diseases are the leading cause of death in patients with non-alcoholic steatohepatitis (NASH). We aimed to investigate the presence of endothelial dysfunction and whether serum concentrations of liver enzymes may reflect the severity of such an endothelial dysfunction in patients with NASH. METHODS Fifty patients with NASH diagnosed by liver biopsies and 30 healthy cont...
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ژورنال
عنوان ژورنال: Journal of Clinical Medicine
سال: 2020
ISSN: 2077-0383
DOI: 10.3390/jcm9123923